Synopsis of GraP

About Gossypium raimondii

Gossypium is the cotton genus. It belongs to the tribe Gossypieae, in the mallow family, Malvaceae, native to the tropical and subtropical regions from both the Old and New World. The genus Gossypium comprises around 50 species, among which G. hirsutum is one of the most important cultivated species. As a "traploid", G. hirsutum has two separate genomes within its nucleus, referred to as the A and D genomes, sharing a high similarity with each other. Gossypium raimondii has a much smaller genome belongs to the D subgenome. To aid understanding of the cotton genome, the genome of G. raimondii was sequenced and assembled.

Why GraP?

At present, research on cotton is mainly focused on genetics and breeding as well as its genetic modification, aiming at improving its stress resistance (especially water stress in high salt, drought or cold environments) and fiber productivity. However, all the biological and physiological mechanisms involved are not well understood. To help researchers uncover the molecular mechanisms related to signal transduction relevant to stress resistance and fiber productivity, a database named GraP (Platform of Functional Genomics Analysis in Gossypium raimondii) was developed to offer users with useful information on functional annotations of genes and proteins.

What is GraP?

In GraP, gene families comprising transcription factors/regulators (TF/TRs), Ubiquitin Proteasome System (UPS), cytochrome p450 and protein kinases/phosphatases are classified and PPIs predicted to help researchers understand gene functions and design experiments more efficiently. Additionally, motif searches upstream of genes are possible for the study of gene co-expression and TF/TRs binding to determine the regulation of gene transcriptional activities. A GSEA web service is included for the mining of functional features of gene lists of interest. In addition, GBrowse, GBrowse_syn and search tools are configured for users to flexibly and directly search for information of their interest.